Lack of association between the prothrombin rs1799963 polymorphism and juvenile myoclonic epilepsy Ausência de associação entre o polimorfismo G20210A (rs1799963) da protrombina e epilepsia mioclônica juvenil

Juvenile myoclonic epilepsy mimicking focal epilepsy Epilepsia mioclônica juvenil imitando epilepsia focal

1Neurology Resident at Santa Marcelina Hospital, São Paulo SP, Brazil; 2Neurologist at Santa Marcelina Hospital, São Paulo SP, Brazil. Correspondence: Valmir Passarelli; Rua Oscar Freire 1.380 / apto. 51; 05409-010 São Paulo SP Brasil; E-mail: [email protected] Conflict of interest: There is no conflict of interest to declare. Received 15 January 2012; Received in final form 27 April 2012; Ac...

Association study between the rs165599 catechol-O-methyltransferase genetic polymorphism and schizophrenia in a Brazilian sample Estudo de associação entre o polimorfismo genético rs165599 da catecol-O-metiltransferase e esquizofrenia em uma amostra brasileira

Schizophrenia is a severe psychiatric disorder characterized by psychotic symptoms and functional impairment, with recurrent relapses and continuing disability. The risk factors for schizophrenia are indicators currently perceived as epiphenomena of pathophysiological processes resulting from geneenvironment interactions that remain poorly understood1. Widespread impairments in brain function a...

Multilocus Genetic Risk Scores for Venous Thromboembolism Risk Assessment

BACKGROUND Genetics plays an important role in venous thromboembolism (VTE). Factor V Leiden (FVL or rs6025) and prothrombin gene G20210A (PT or rs1799963) are the genetic variants currently tested for VTE risk assessment. We hypothesized that primary VTE risk assessment can be improved by using genetic risk scores with more genetic markers than just FVL-rs6025 and prothrombin gene PT-rs1799963...

Association study between the Taq1A (rs1800497) polymorphism and schizophrenia in a Brazilian sample Estudo de associação entre o polimorfismo genético Taq1A (rs1800497) e esquizofrenia em uma amostra brasileira

Schizophrenia is a severe psychotic disorder with recurrent relapse and functional impairment. It results from a poorly understood geneenvironment interaction. The Taq1A polymorphism (located in the gene cluster NTAD) is a likely candidate for schizophrenia. Its rs1800497 polymorphism was shown to be associated with DRD2 gene expression. Therefore the present work aims to investigate a possible...

Climacteric Symptoms and Sexual Dysfunction: Association between the Blatt-Kupperman Index and the Female Sexual Function Index Sintomatologia climatérica e disfunção sexual: associação entre o índice de Kupperman e Blatt e o índice de função sexual feminina